Curcumin 500 with Bioperine®
Curcumin 500 with Bioperine®
Brief Description: Curcumin 500 with Bioperine
Per Bottle: 60 or 120 Vegetarian Capsules
Contains no yeast, wheat, gluten, milk/dairy, sodium, corn, sugar, starch, artificial coloring, artificial preservatives, artificial flavoring, or genetically modified organisms (GMOs).
- Contains Bioperine (a black pepper extract) to promote curcumin absorption
- Healthy liver, colon, musculoskeletal and cell function*
- Cognitive function in healthy aging adults
- Helps enhance antioxidant defense 7 reduce inflammation*
- Made with hypoallergenic, vegan ingredients
Curcumin is a potent extract form the turmeric root with many health benefits.
Curcumin with Bioperine (a black pepper extract) promotes the absorption of curcumin to help support liver, colon and musculoskeletal health as well as cell function. Curcumin with Bioperine provides enhanced bioavailability for optimal cellular support.*
Turmeric consists of many curcuminoids including the one you may be familiar with already: curcumin. Curcumin has been shown to have potent antioxidant activity, and several factors contribute to that.
Curcumin has a long history of use for supporting healthy cyclooxygenase, prostaglandin and leukotriene metabolism. It also appears to provide important antioxidant defense. Furthermore, it supports the body's natural detoxification system and helps maintain healthy hepatic function. These actions are associated with its beneficial effects, including support for healthy liver, colon, musculoskeletal and cellular function.
Curcumin C3 Complex® has been the subject of scientific investigations at a number of hospitals and universities. Most recently, it has demonstrated the potential to maintain healthy tissue in the brain by supporting macrophage activity and has been associated with powerful support for cellular health in separate trials. Bioperine® is a black pepper extract that contains the alkaloid piperine. Research reveals that it has the potential to enhance the bioavailability of curcumin, promoting its absorption.
Curcumin can help the body scavenge various reactive oxygen and nitrogen species (including superoxide anions, hydrogen peroxide, and nitrite radicals) that are produced by activated immune cells, such as macrophages, and ordinarily go on to damage protein, lipids, and DNA in our cells.
Curcumin helps stimulate a very important genetic pathway known as the NRF2 pathway, which activates a whole set of antioxidant genes, including genes like glutathione synthase (which is the body’s natural way of making glutathione) and glutathione peroxidase (which is the way the body uses glutathione to fight off damage) and is just one way that curcumin fights damaging oxidants.
What this means is this: while your immune system is doing what it is supposed to do in order to keep out foreign or unhealthy invaders, the curcumin negates some of those bad side-effects that occur due to an activated immune response. It does this by helping keep the inevitable reactive oxygen and nitrogen species we all have to a minimum, which is also one of the mechanisms by which curcumin has been shown to prevent unhealthy cells from forming.
Turmeric and its associated curcuminoids also have excellent effects on the brain. When microglial cells, which are the immune cells of the brain, are activated this generates the same type of damaging reactive oxygen and nitrogen species (mentioned above) that cause the aggregation of amyloid beta and tau plaques in the brain.
These toxic plaques are associated with age-related cognitive decline and even traumatic brain injury. The activated microglial cells and this entire damaging process are referred to, generally, as neuroinflammation. Curcuminoids in turmeric have been shown to be able to cross the blood-brain barrier and help the body reduce neuroinflammation which has been linked to cognitive challenges.
In fact, curcumin from turmeric has been demonstrated to inhibit the aggregation of amyloid beta protein, which leads to plaques in the brains of people with unhealthy brain conditions.
Another powerful brain benefit of turmeric in addition to reducing neuroinflammation is that it also contains a curcuminoid called ar-turmerone which has been shown to increase the production of neural stem cells in the brain.
This means that the turmerone in turmeric has the potential to not only prevent the initial damaging process of neuroinflammation we talked about a moment ago but even after the fact shows promise in replacing those same damaged neurons.